Single cell genomic platforms off unprecedented ability to characterise heterogeneity of cell populations. We are applying single cell RNA and ATAC sequencing to understand human immune response to malaria infection. Our key goals are to identify key cellular subsets and responses that drive the induction of protective immunity. We use multiple human malaria cohorts, including controlled human malaria infection models, and cohorts of children and adults from different malaria transmission settings. This project will suit a student with strong background in bioinformatics and/or computational biology who is interested in applying single cell technologies to human immunology.
Michelle Boyle | Michelle.firstname.lastname@example.org