Student Projects

We have a wide range of student projects, and many can be tailored to a student’s project research interests. View a list of projects available to students studying their PhD, Honours or Masters.

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Mental Health & Neuroscience

The potential impact of bushfire smoke on brain health

This project is suitable for Honours, Masters, MPhil, MD or PhD student. Background In this project, we are using our monocyte and pluripotent stem cell-derived brain cell models to understand how bushfire smoke affects the human brain, particularly its ability to include neuroinflammation. We are also working with Assoc. Prof. Michelle Lupton, and Dr Jodi […]

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Drug repurposing to treat childhood dementia

This project is suitable for Honours, Masters, MPhil, MD or PhD student. Background Childhood dementia is caused by a group of genetic disorders which have effects on infants and children that include dementia (loss of normal brain function). There are no cures, and treatments limited effects. We are collaborating with Prof. Eske Derks and Dr […]

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Using large scale genetic data to understand cholinergic dysfunction in Alzheimer’s diseases

This project is suitable for Honours, Masters, MPhil, MD or PhD student. For those with experience in coding and statistics, and an interest in dementia, genetic epidemiology, and bioinformatics. Background Cholinesterase inhibitors are the primary drugs currently used for the treatment of Alzheimer’s disease (AD), but the exact mechanism of action is unclear. Gaining a […]

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Methylation-based biomarkers for Alzheimer’s disease

This project is suitable for Honours, Masters, MPhil, MD or PhD students. For those with experience in coding and statistics, and an interest in dementia, DNA methylation analysis, genetic epidemiology, and bioinformatics. Background DNA methylation (DNAm) patterns derived from blood samples correlate strongly with chronological age, thereby referred to as the ‘epigenetic clock’. Epigenetic clocks […]

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Modelling neural circuit control of effort under stress

This project is suitable for Honours, Masters, or PhD student Background The decision to put in effort to attain rewards is essential for success in life, and critical for survival. Yet, we understand very little about the brain processes that promote persistence and enable individuals to ‘keep going’ instead of ‘give up’ when increasing amounts […]

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Genetic and environmental influences on brain structure and function

The project is suitable for an Honours student. Background Genetic and environmental factors influence the structure and function of the human brain. Disentangling and quantifying these sources of variation (genetic and environmental) may be crucial to understanding the brain’s genetic architecture and how it relates to typical and atypical brain function. Aim To provide a […]

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Physiological signal analysis from infancy to adolescence

Suitable for PhD, Masters or Honours students. The advent of precision medicine demands better tools for measuring human structure and function. A particularly important period of development where this lack of diagnostic and prognostic tools is felt in earnest, is the period from infancy to adolescence. We measure the function of the brain, heart and […]

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Identifying risk factors for problematic internet use and video gaming in Australian adults

Suitable for Honours students only. This project is most suitable for students with a strong background in Psychology/Psychiatry and statistical analysis. The proliferation of computers, gaming consoles and widespread use of the internet in the last 15 years has resulted in the emergence of behavioural addictions to digital technology, namely the internet and video games, […]

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Generating Alzheimer’s microglia for testing patient responses to immune-modulating compounds

This project is suitable for a PhD or Honours student. Alzheimer’s disease is anticipated to affect 100 million patients with an annual cost of US$1 trillion by 2050. Promising amyloid-clearing therapies have failed to translate to clinical outcomes, and new approaches targeting the underlying molecular pathways of Alzheimer’s disease are urgently required. There has been […]

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