Student Projects

Infectious Diseases

Scabies Group: Determination of the antimicrobial effects of novel acaricides

Honours project only Scabies and associated co-infections cause substantial illness and a major health burden in Indigenous communities of Northern Australia. In particular scabies-caused childhood pyoderma (bacterial skin infection) can cause severe complications in later life. Scabies-associated Streptococcus infections for example, significantly contribute to an immune complication of streptococcal infection that leads to heart and […]

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Human Malaria Immunology Group: Single cell genomic technologies in human malaria immunology

Projects can be adapted to suit Honours, Masters and PhD level students Single cell genomic platforms off unprecedented ability to characterise heterogeneity of cell populations. We are applying single cell RNA and ATAC sequencing to understand human immune response to malaria infection. Our key goals are to identify key cellular subsets and responses that drive […]

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Immunology & Infection Laboratory: Discovering novel immunoregulatory molecules that can be manipulated for clinical advantage

Diseases caused by intracellular protozoan parasites that cause malaria and leishmaniasis require the generation of CD4+ T (Th1) cells that produce pro-inflammatory cytokines. These molecules stimulate dendritic cells (DCs) and macrophages to expand CD4+ T cell responses and activate phagocytes to kill captured or resident pathogens. However, the inflammatory cytokines produced by Th1 cells also […]

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Molecular Parasitology Group: New interventions to end neglected tropical diseases in Asia

Suitable for PhD students only The Neglected Tropical Diseases (NTDs) are a group of parasitic/bacterial diseases that cause substantial morbidity for more than one billion people globally. Affecting the world’s poorest people, NTDs cause severe disability, hinder growth, productivity and cognitive development, and often end in death; children are disproportionately affected. Asia is a NTD […]

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Molecular Parasitology Group: Development of new interventions including vaccines, DNA diagnostics and serological markers essential for ending neglected tropical diseases caused by schistosomes and intestinal worms in Asia and Africa

Suitable for PhD students only The Neglected Tropical Diseases (NTDs) are a group of parasitic/bacterial diseases that cause substantial morbidity for more than one billion people globally. Affecting the world’s poorest people, NTDs cause severe disability, hinder growth, productivity and cognitive development, and often end in death; children are disproportionately affected. Asia is a NTD […]

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Molecular Parasitology Group: Establishment of a CRISPR- Cas9-mediated gene knock- down system in Schistosoma japonicum targeting the acetylcholinesterase gene

Suitable for PhD students only Schistosomiasis is a serious global problem and the second most devastating parasitic disease following malaria. Currently, there is no effective vaccine available and treatment is entirely dependent on praziquantel chemotherapy, raising a significant threat to public health. The paucity of molecular tools to manipulate schistosome gene expression has made an […]

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