Student Projects

We have a wide range of student projects, and many can be tailored to a student’s project research interests. View a list of projects available to students studying their PhD, Honours or Masters.

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Developing small molecule inhibitors to target treatment refractory melanoma.

This project is suitable for PhD students. Background Cutaneous melanoma is a neoplasm of melanocytes, the pigment producing cells in the skin, and is the most aggressive and lethal form of skin cancer. The incidence of melanoma has increased dramatically over the past three decades, including in Australia where it is now the fourth most […]

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ASCENT: Randomised controlled feasibility trial to investigate the impact of prepartum antibiotics exposure on childhood allergy

This project is suitable for PhD students. Background Early life from conception to infancy is a delicate stage where the immune system is highly susceptible to the environment. This project was initiated in response to concerns about the routine use of antibiotics during scheduled caesarean sections, despite their known impact on newborns’ microbiota and immune […]

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Unravelling the Genetic & Environmental Basis of Chronic Pain

The scope of this project can be adapted to PhD, MPhil, or Honours. Background Chronic pain is a complex condition that significantly diminishes the quality of life of those affected and imposes a heavy burden on healthcare systems globally. Despite its widespread impact, the genetic and environmental contributors to chronic pain are not well understood. […]

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The potential impact of bushfire smoke on brain health

This project is suitable for Honours, Masters, MPhil, MD or PhD student. Background In this project, we are using our monocyte and pluripotent stem cell-derived brain cell models to understand how bushfire smoke affects the human brain, particularly its ability to include neuroinflammation. We are also working with Assoc. Prof. Michelle Lupton, and Dr Jodi […]

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Mosquito-borne disease transmission in a changing world

Background In recent decades, arthropod-borne viruses (arboviruses) have emerged or re-emerged as human and animal pathogens with important implications for public health. These include dengue, Zika and chikungunya viruses, which circulate between humans and the urban mosquitoes, Aedes aegypti and Aedes albopictus, as well as zoonoses with complex transmission pathways that involving multiple vectors and […]

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Drug repurposing to treat childhood dementia

This project is suitable for Honours, Masters, MPhil, MD or PhD student. Background Childhood dementia is caused by a group of genetic disorders which have effects on infants and children that include dementia (loss of normal brain function). There are no cures, and treatments limited effects. We are collaborating with Prof. Eske Derks and Dr […]

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Using large scale genetic data to understand cholinergic dysfunction in Alzheimer’s diseases

This project is suitable for Honours, Masters, MPhil, MD or PhD student. For those with experience in coding and statistics, and an interest in dementia, genetic epidemiology, and bioinformatics. Background Cholinesterase inhibitors are the primary drugs currently used for the treatment of Alzheimer’s disease (AD), but the exact mechanism of action is unclear. Gaining a […]

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Methylation-based biomarkers for Alzheimer’s disease

This project is suitable for Honours, Masters, MPhil, MD or PhD students. For those with experience in coding and statistics, and an interest in dementia, DNA methylation analysis, genetic epidemiology, and bioinformatics. Background DNA methylation (DNAm) patterns derived from blood samples correlate strongly with chronological age, thereby referred to as the ‘epigenetic clock’. Epigenetic clocks […]

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Modelling neural circuit control of effort under stress

This project is suitable for Honours, Masters, or PhD student Background The decision to put in effort to attain rewards is essential for success in life, and critical for survival. Yet, we understand very little about the brain processes that promote persistence and enable individuals to ‘keep going’ instead of ‘give up’ when increasing amounts […]

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