Histology

Histological samples are critical to observing the appearance of normal vs. diseased cells in microscopic detail. Knowing what normal tissue looks like and how it normally works is important for recognising different diseases. We cater to the needs of scientists based onsite, and other national and international institutions. We are committed to excellence, quality, consultation, clinical evaluation and collaboration.

The histology facility provides technical services and also trains and consults on matters relating to:

  • Routine paraffin and cryo histology
  • Special stains (e.g. Masson’s, Sirius Red, Perl’s)
  • Immunohistochemistry (Tyramide Signal Amplification) and antibody optimisation
  • FISH and CISH labelling
  • TMA preparation and high-resolution digitisation of histology slides (e.g. Vectra Imaging System).

The facility stocks a broad selection of commonly used primary antibodies and secondary detection antibodies to label mouse, rat, rabbit, goat, sheep, hamster, guinea pig and chicken primary antibodies with horseradish peroxidase, alkaline phosphatase, Alexa fluorescent or Tyramide (TSA) markers.

CONTACT

Andrew Masel
Manager
T +61 7 3845 3873
E Histology@qimrberghofer.edu.au

The facility has a comprehensive range of equipment for paraffin and frozen sample processing and microtomy, automated slide dewaxing and staining.

Equipment at the facility includes:

  • Excelsior ES tissue processors
  • Tissue-Tek TEC paraffin embedding station
  • ST5010 Autostainer XL
  • CV5030 Robotic Coverslipper
  • RM2235 rotary microtomes
  • Slide and cassette writers
  • Cryostar NX70 Cryostat
  • Ventana Discovery Ultra automated IHC stainer
  • Biocare Medical IntelliPath semi-Automated IHC stainer
  • Vibratome NVSL
  • Beecher Tissue MicroArrayer
  • Clay Winterford
  • Sang-Hee Park
  • Crystal Chang