People with decompensated cirrhosis require complex medical care and are often prescribed an intricate and frequently changing medication and lifestyle regimen. However, many patients mismanage their medications or have poor comprehension of their disease and self-management tasks. This can lead to harm, hospitalization, and death.
We are conducting a patient-oriented education and medication management intervention at a tertiary hospital hepatology outpatient clinic in Queensland, Australia. Consenting patients with decompensated cirrhosis are randomly allocated to education intervention or usual care treatment arms when they attend routine follow-up appointments. In the usual care arm, participants are reviewed by their hepatologist according to the current model of care in the hepatology clinic. In the intervention arm, participants are reviewed by a clinical pharmacist to receive the education and medication management intervention at baseline in addition to review by their hepatologist. Investigation of potentially modifiable variables that may impact medication management, in addition to the effect of a clinical pharmacist-driven education and medication management intervention on modifying these variables, will provide valuable information for future management of these patients.