Dr Michelle Lupton area of expertise is genetics of neurodegenerative and psychiatric disease, with her main focus on Alzheimer’s disease. She has a strong track record in Genome Wide Association Studies (GWAS) and next generation sequencing studies being an active member of the world leading research consortia. She has been part of the major discoveries in Alzheimer’s disease genetics of the past decade, including the identification of the first genome wide significant genetic risk variants outside of APOE, and the discovery of the large effect rare variants of TREM2 using exome sequencing.
Michelle’s current research focus aims to improve understanding of the early effect of AD genetic risk factors, and identify biomarkers before clinical diagnosis. She is currently a research fellow and the genetics and epidemiology analyst for the Prospective Imaging Study of Aging: Genes, Brain and Behaviour (PISA). She also have an interest in Alzheimer’s disease biomarkers, genetic risk prediction and the use of genetic risk variants to identify prodromal disease markers.
Current QIMR Berghofer appointment
- 2017 – Present: Senior Research Officer, Genetic Epidemiology
- 2018 – Present: NHMRC Boosting Dementia Leadership Fellow.
Other current appointments
- 2018 – Present: Adjunct Associate Professor, School of Biomedical Sciences, Queensland University of Technology (QUT)
- 2015– Present: Visiting Academic, Queensland Brain Institute, University of Queensland (UQ)
- 2012 – 2017: Research Officer, Neuroimaging Genetics and Genetic Epidemiology QIMR Berghofer.
- 2009 – 2012: Post-Doctoral Research Worker, Kings College London (KCL) UK.
- 2011 – 2012: Demonstrator for Advanced Research Methods, Psychology Undergraduate Certificate Programme, Birkbeck University of London, UK.
- 2006 – 2009: MRC funded capacity building PhD Studentship, Neuroscience, Kings College London (KCL), UK.
- 2004 – 2006: Research Assistant, Medical and Molecular Genetics, Kings College London (KCL), UK
Michelle’s current h-index is 36. She has 40 peer reviewed publications, including 2 review articles, and 38 original research articles as a named author, many of which are in high impact journals. Presently she has 8 first author publications.
- 2019 – current: Member of the National Institute for Dementia Research (NNIDR) Early/Mid career Accelerator Working Group (providing capacity building and career support to NNIDR’s cohort of Development Fellows in Australia)
- 2013-2020: Member and Communications manager of the QIMR Berghofer Postdoctoral committee and organiser of post-doctoral forums in 2013, 2014 and 2017
- She is currently a member of the Australian Society for Medical Research (ASMR), the International Society to Advance Alzheimer’s Research and Treatment (ISTAART), the American Society of Human Genetics (ASHG), and the Australian Epigenetics Alliance (AEpiA).
- 2018: NHMRC Boosting Dementia Research Leadership Fellowship
- 2012: QIMR Early Career Postdoctoral Fellowship from the Perpetual Foundation
- 2016: The Australian Society for Medical Research Senior Researcher Award Finalist
- 2011: International Congress of Human Genetics trainee research award semi-finalist
- 2009: Kings College London Health Schools graduate showcase oral presentation prize
- 2003: BSc Honours Human Genetics, University of Nottingham, UK
- 2010: PhD Neuroscience, Kings College London (KCL), UK.