Dr Leon Hugo
Current Area of Research
Leon researches the entomological factors affecting mosquito-borne disease. He investigates the susceptibility and vector competence of mosquitoes to established and emerging arboviruses (dengue, chikungunya, Ross River and Zika viruses) and conducts research into new surveillance and disease control opportunities.
Leon is working within the INTERfering and Co-Evolving Preventive and Therapeutics (INTERCEPT) program of the US Defence Advanced Research Projects Agency (DARPA). In collaboration with the Queensland University of Technology, MCL is investigating Dengue virus Transmissible Interfering Particles (TIPs), which are sub-genomic particles that have the potential to attenuate viraemia and curtail transmission. Leon has recently been involved with the development of transmission models for chikungunya virus and Plasmodium (in the context of human malaria clinical trials). He has guided collaborative projects in areas of mosquito vector competence, molecular ageing in mosquitoes, the ecology of Wolbachia and protein biomarker discovery.