Professor | Deputy Director | Coordinator of the Cell & Molecular Biology Department | Senior Principal Research Fellow | Group Leader+61 7 3362 0177
Professor Grant Ramm is a graduate of the University of Queensland with BSc (Hons) and PhD. He is Head of the Hepatic Fibrosis Laboratory and Coordinator of the Cell and Molecular Biology Department and is a Senior Principal Research Fellow at QIMR Berghofer.
His research at QIMR Berghofer has included investigation into the molecular, cellular and histopathological events involved in initiating hepatic fibrosis (liver scarring) in chronic liver disease associated with both hereditary haemochromatosis in adults and Cystic Fibrosis in children. Mechanistic evaluation of these cellular events will aid in identifying patients at risk of serious liver disease complications (including cirrhosis and liver cancer) and lead to the development of new biomarkers as well as novel therapeutic interventions to treat chronic liver disease.
2020-current: President, Organising Committee for World Congress of Iron metabolism – BioIron 2022
2020–current: Senior Principal Research Fellow (SPRF)
2016–current: Editor-in-Chief for Journal of Renal and Hepatic Disorders
2013–current: Member, Research Advisory Committee of the Royal Brisbane and Women’s Hospital (RBWH)
2012–current: Coordinator, Cell and Molecular Biology Department
2012–current: Professor, School of Medicine, (Faculty of Health Sciences), The University of Queensland
2005–current: Member, Board of Management of the Liver Foundation
1996–current: Group Leader of the Hepatic Fibrosis laboratory
2015: NHMRC Assigners Academy Member (Development Grants)
2014–2016: NHMRC Assigners Academy Member (Project Grants)
2014: NHMRC Program Grant Review Panel (PGRP) Member for review of NHMRC Program Grants for 2016
2013: NHMRC GRP Panel 3E (Endocrinology, Diabetes, Gastroenterology, Nutrition, Obesity) Member for review of NHMRC research project grants
2012: NHMRC GRP Panel 6E (Endocrinology, Diabetes, Gastroenterology, Nutrition, Obesity) Member for review of NHMRC Research Project grants
2011: Visiting Professor, Chinese Academy of Science (CAS), National Center for Nanoscience and Technology of China
2011–2014: Steering Committee Member, Asian-Pacific Association for the Study of the Liver (APASL) 2014 Conference Steering Committee
2010–2011: Member, Local Organising Committee for inaugural international LiverDownUnder conference (FASEB-affiliated meeting)
Professor Ramm’s research interests are in both the mechanism, and clinical translation, of research into chronic liver disease, particularly hereditary haemochromatosis (most common genetically inherited disease in caucasians), paediatric CF-associated liver disease (most common lethal inherited disease) and more recently in liver cancer (now the 2nd most common cause of cancer-related death worldwide). His expertise lies in the cellular and molecular biology of hepatic fibrogenesis (liver scarring), i.e. understanding disease mechanisms and pathways, and applying this knowledge to the early detection, monitoring progression, predicting outcome and therapeutic potential of these research discoveries. Professor Ramm’s specific cells of interest are the resident liver myofibroblast precursors, the hepatic stellate cell, and their interaction with liver stem cells in driving inflammation, fibrogenesis, liver regeneration and ultimately in fibrosis, cirrhosis and the development of liver cancer.
2020: Promoted to Senior Principal Research Fellow at QIMR Berghofer
2019: Long service award by QIMR Berghofer
2014: Promoted to NHMRC Senior Research Fellow (Level B)
2014: Promoted to Principal Research Fellow at QIMR Berghofer
2014: Awarded Fellowship of the American Association for the Study of Liver Disease (FAASLD) for “Significant contributions to the science and practise of hepatobiliary diseases”
2012: Promoted to Professor, School of Medicine (Faculty of Health Sciences), The University of Queensland.
2012: Appointed Head of Department – Cell and Molecular Biology, QIMR.
1993: Doctor of Philosophy (PhD) – The University of Queensland (Medicine).
1982: Bachelor of Science with Honours (BSc (Hons)) – The University of Queensland (Biochemistry).
1981: Bachelor of Science (BSc) – Double Major in Biochemistry and Microbiology – The University of Queensland