Associate Professor | Group Leader+61 7 3845 3950
2012-2017: Team Head, QIMR Berghofer Medical Research Institute
2004-2012: Research Officer and Senior Research Officer, Peter MacCallum Cancer Centre
2003-2004: Postdoctoral Researcher, University of Berne
Associate Professor Andreas Moller leads the Tumour Microenvironment Laboratory, which focuses on advancing our understanding of the communication between cancer cells and their environment. A solid tumour consists of many normal cell types in addition to the malignant cancer cells, and these normal cells largely determine the progression of the cancer. The laboratory was the first to show that this communication of cancer cells, initiate by low oxygen environments within the tumour, causes the formation of permissive environments in distant organs, which are prerequisites for metastasis.
Currently, Associate Professor Moller and his lab is delineating the communication between the malignant cells and normal, especially immune, cells at metastatic sites. Development of novel therapeutic and diagnostic capacity, which is partly based on small vesicles, termed exosomes, secreted by cancer cells is also an important priority.
Overall, the group is focussed on translational cancer research, with a focus on metastasis, cellular communication, immune regulation and extracellular vesicles, mostly concentrating on solid malignancies, including breast and lung cancer.