In the majority of cases, QIMR Berghofer's clinical trial participants are recruited through referral by registered healthcare providers, such as GPs and specialists. If you are interested in being involved in clinical trials, the first step is to search the Australia and New Zealand Clinical Trial Register, which maintains a comprehensive directory of all trials being conducted in Australia and New Zealand. Having identified an appropriate trial in the register, you can then discuss your potential candidacy with your registered healthcare provider.
There are other clinical trials and research studies being conducted by QIMR Berghofer that may be relevant for you or someone you know. These select trials and studies, listed below, enable you to register your interest directly with the Institute.
Glaucoma is a leading cause of blindness worldwide. Genetics play a major role in determining who will and will not be affected by glaucoma. Identifying glaucoma risk genes will help us identify the people at highest risk of developing glaucoma, enabling more efficient disease screening. Glaucoma is typically treatable if diagnosed in time, so ultimately we hope this work will help prevent irreversible blindness.
About the study
We aim to identify glaucoma risk genes and to develop a genetic risk prediction tool to identify people at high risk of developing glaucoma. As well as improving screening, identifying glaucoma risk genes is likely to help us understand this biological basis of the disease and this may help us identify candidate drugs that can help control glaucoma. For more information about our latest work on glaucoma, please read this LIFELAB article.
We are seeking people aged 18 years and above who have been diagnosed with glaucoma by an ophthalmologist or optometrist, have been prescribed a glaucoma medication, or have family history of glaucoma.
How to participate
Australian Genetics of Bipolar Disorder Study
We are recruiting people who have been treated for Bipolar disorder for a new study seeking to find genetic risk factors influencing Bipolar disorder. We are also looking for genetic markers that influence response to treatment or lead to an increased risk of side effects.
The long term aims are to be able to use this information to help speed up the process of diagnosing bipolar disorder and identifying the best treatment strategies at an individual level.
Study participation involves completing an online questionnaire and providing a saliva sample (in a tube that we send out).
There is more information about the study and what is involved in participating on the study webpage - https://www.geneticsofbipolar.org.au/ , please click the button below to access this site.
QIMR Berghofer is leading the largest study of asthma genetics in Australia to identify genes that increase a person's risk of developing asthma. We are looking for people who have had asthma, but no longer experience symptoms to participate in the study. Free call 1800 257 179 or visit the asthma study website for more information.
The purpose of this research project is to identify genetic factors and biological pathways that influence the risk in epilepsy. It will also investigate the effectiveness and tolerance of medications for epilepsy.
We are seeking healthy adults to volunteer for an exciting study on brain function and connectivity.
Healthy brain function relies on the coordinated transfer of information between separate brain regions. If this communication becomes chronically disrupted, it can result in various psychological conditions such as depression and obsessive compulsive disorder.
Our research takes the first step toward understanding these disrupted communication patterns by mapping functional brain activity in healthy individuals.
To be eligible for this study, you will:
- Be aged 18 to 35
- Have no history of neurological disorders or mental illness
- Have no personal, or family history of seizures or epilepsy
- Be willing and eligible for an MRI and transcranial magnetic stimulation
The study will involve 3 visits to QIMR Berghofer. On the first visit, you will have a 45 minute magnetic resonance imaging (MRI) scan to provide us with a 3D model of your brain and a snapshot of your brain activity at rest. During the next two visits, we will stimulate your brain using transcranial magnetic stimulation (TMS) to temporarily change the communication patterns between certain brain regions. We’ll use electroencephalography (EEG) to monitor these changes in real time to see how the brain regions ‘talk’ to each other.
As thanks for your participation, you will receive a $75 Coles-Myer gift card for the three study sessions ($25/session).
If you would like to participate, please contact Stacey Logan via email Stacey.email@example.com
The Gut-Brain Connection: understanding the relationship between the gut microbiome and the brain
Researchers at QIMR Berghofer Medical Research Institute are seeking healthy adults, as well as individuals diagnosed with Inflammatory Bowel Disease (IBD), to participate in a study investigating the relationship between the gut microbiome and the brain. In particular, the researchers are interested in how the gut impacts the way your brain functions, and to test whether this is intricately linked to levels of anxiety and stress. Find out more about the study and how to participate, or contact the Study Coordinator directly at firstname.lastname@example.org.
Genetics of risk and response to treatment of depression
The purpose of this research project is to identify specific genetic risk factors associated with risk of depression, as well as factors associated with response to treatment. We hope that this research will help us learn more about depression and the factors influencing why various treatments are successful for some people and not others. Read more.
Future mental health studies
We are also recruiting older healthy volunteers to participate in mental health studies. If you wish to register now, we will keep your name and contact details in a secure database and contact you when we have an upcoming experiment that may be suitable.
Email email@example.com and provide your name, address, date of birth and phone number. We will contact you before any potentially suitable experiments and send you a brief health screening questionnaire and participant information sheet.
We are looking for young, healthy people who are interested in making a valuable contribution to mental health research.
Mental health affects everyone and can have a devastating effect on the individual and the community. Psychosis (disorganisation of thought, experience, and emotion) tends to first present in young people as the brain is maturing.
We want to find out why, and we need your help. We are looking for “Healthy Controls” to participate in our study comparing to other individuals presenting with mental illness for the first time.
We are looking for participants with the following eligibility criteria:
- You are aged between 16 and 25
- Have no history of mental health condition
- Have no first degree relative with severe mental illness
- Have no history of neurological condition or serious head injury
- Have no history of HIV, Hepatitis B, C, or chronic infective condition
- Have no history of diabetes, high cholesterol or hypertension
Each time point involves a 60 minute cognitive and IQ test, a 60 minute MRI and an optional 30 minute additional scan. We will also capture demographics and substance use history, parent's permission if under 18 and your contact details for follow up.
You will receive a $50 Coles Myer Gift Voucher for your help in the study.
To participate, please contact the Principal Investigator via email on firstname.lastname@example.org.
QIMR Berghofer has a new study that aims to identify risk factors that will help predict which women may be at risk of developing severe morning sickness. The study's goal is to improve the treatment options for women with severe morning sickness, by allowing earlier intervention. If you are over 18 and have been pregnant at least once, find out more about participating in this study, or email email@example.com.
OBSESSIVE COMPULSIVE DISORDER (OCD)
QIMR Berghofer has a new study that seeks men and women between the ages of 18 and 50 who have been diagnosed with OCD for at least 12 months. Participants are required to attend 24 study site visits over 6 weeks, along with a 25th visit after 6 months. Participants will be offered parking/transport vouchers (up to 40 AUD per visit). Please click the button below or visit the Obsessive-Compulsive Disorder Clinical Trial webpage for more detailed information. You can also email firstname.lastname@example.org.
Twin studies (QTwin)
The Queensland Twin Registry (QTwin) is a population-based registry of identical and non-identical twins. We are currently seeking participants:
- from South-East Qld - identical or non-identical twins eight years and older
- from Qld, NSW and Vic - identical or non-identical twins aged 65-90 years.
Free call 1800 257 179 to be automatically directed to twin studies in your area.