The Respiratory Immunology Laboratory focuses on identifying pathogenic pathways that underpin the onset, progression, and exacerbations of asthma and chronic obstructive pulmonary disease. To achieve this, high-fidelity preclinical models of disease are developed that recapitulate key gene-environment interactions and allow for elucidation of cellular and molecular mechanisms. Where possible, scientific findings are translated with ex vivo model systems using primary human cells and by analysing clinical material.
External Collaborators