Respiratory Immunology

The Respiratory Immunology Laboratory focuses on identifying pathogenic pathways that underpin the onset, progression, and exacerbations of asthma and chronic obstructive pulmonary disease. To achieve this, high-fidelity preclinical models of disease are developed that recapitulate key gene-environment interactions and allow for elucidation of cellular and molecular mechanisms. Where possible, scientific findings are translated with ex vivo model systems using primary human cells and by analysing clinical material.

CURRENT RESEARCH

  • insights into the influence of maternal diet on the severity of infant RSV bronchiolitis
  • regulation of HMGB1 and IL-33 release
  • microbiota and immune cell development in early life
  • eicosanoids and viral exacerbations of COPD

Staff

  • Dr Ashik Ullah, Research Officer
  • Lisa Bain, Research Assistant
  • Dr Ismail Sebina, Research Officer
  • Ridwan Rashid, PhD Student
  • Muhammed Rahman, PhD Student

External Collaborators

  • Dr Paul Dennis, University of Queensland
  • Paraic O’Cuiv, University of Queensland
  • Sumaira Hasnain, Mater UQ
  • Dr Henry McSorley, The University of Edinburgh
  • Professor Mark Everard, University of Western Australia
  • The National Health and Medical Research Council