The Iron Metabolism Laboratory studies a wide spectrum of iron-related issues from basic mechanisms of iron homeostasis to disorders of iron metabolism. We are interested in iron nutrition and iron deficiency, diseases of iron loading (haemochromatosis, thalassaemia), perinatal iron metabolism, and the use of nanotechnology to modulate body iron levels. The laboratory integrates genetic and molecular studies with biochemical and physiological approaches. We have a particular interest in understanding how the liver-derived hormone hepcidin regulates body iron homeostasis. The ultimate goal of our work is to improve the diagnosis and treatment of a range of conditions where iron metabolism is perturbed.