Prostate cancer is the most commonly diagnosed cancer in Australian men, with more than 16,000 new cases estimated in 20201. One in six men will be diagnosed with prostate cancer by the age of 85.2
When diagnosed early, prostate cancer is curable, and 95% of patients diagnosed with prostate cancer are expected to survive at least five years post-diagnosis. Nevertheless, prostate cancer is the second most common cause of cancer death among males in Australia with more than 3,000 Australian men expected to die from prostate cancer each year.3 Prostate cancer spreading is a major cause of mortality.
With the excellent prognosis, more than 220,000 Australian males are estimated to be living with prostate cancer as at 2015.4
With many Australian men living with prostate cancer, quality of life is a key consideration of prostate cancer management.
Prostate cancer is slow-growing in its early stages, and can be managed by watchful waiting and active surveillance, to avoid undesired treatment side effects.
However, prostate cancer that spreads to other organs (metastatic prostate cancer), most commonly the bone and lymph nodes, have poor prognosis. Therefore, it is important to understand the process of prostate cancer metastasis, in order to develop strategies to prevent it.