The Cancer Neuroscience Lab aims to translate insights from fundamental neuroscience research and apply these to brain cancer, with a particular interest in glioblastoma, which is the most common malignant primary brain tumour in adults and has a median survival of just 15-months after diagnosis. At the core of The Cancer Neuroscience lab is a focus on researching cellular quiescence, a reversible hibernation-like state, adopted by brain cancer cells to evade chemotherapy and radiotherapy. By targeting these quiescent cells, we might overcome treatment resistance and improve outcomes for persons with glioblastoma. To identify novel therapeutic approaches to target quiescence, the lab also focuses on understanding how quiescence is regulated in normal neural stem cells in the memory centres of our brains.
We gratefully acknowledge the support of the following funding agencies: