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Cancer Metabolism

Dr Nils Halberg

Group Leader

The Cancer Metabolism laboratory primarily studies cancer cells and the surrounding microenvironment adapt to changes in diet and physiological homeostasis. 

 

CURRENT RESEARCH

Our major current focus is to delineate the molecular mechanisms by which obesity causes cancer. This includes obesity-dependent regulation of cell-cell interactions within the tumor ecosystems as well as epigenetic control of cancer cell subpopulation dynamics. 

External Collaborators

  • Philipp Scherer, UTSW
  • Rolf Brekken, UTSW
  • Srinivas Malladi, UTSW
  • Sarah Fendt, KU Leuven
  • Colinda Schele, KU Leuven
  • Jim Lorens, University of Bergen
  • Anders Molven, University of Bergen
  • Stian Knappskog, University of Bergen
  • Ivonne Regel, University of Munich
  • Caroline Verbeke, University Hospital Oslo
  • Norwegian Research Council
  • Norwegian Cancer Society
  • Novo Nordisk Foundation
  • Marie Curie Fellowship

STUDENT PROJECTS

Mechanistic understanding of how obesity causes cancer – Research project #3: How does physiological stressors affect somatic fully differentiated cells of the body?

Obesity increases the risk of developing thirteen types of cancer that normal weight individuals may not develop despite of harbouring the same cancer risk loci. Globally, overweight/obesity may account for 544 300 cancer cases every year and is currently implicated in 15-20% of cancer-related mortalities. This places obesity second only to smoking as the most […]

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Mechanistic understanding of how obesity causes cancer – Research project #2: How do physiological stressors affect the tumor ecosystem?

Obesity increases the risk of developing thirteen types of cancer that normal weight individuals may not develop despite of harbouring the same cancer risk loci. Globally, overweight/obesity may account for 544 300 cancer cases every year and is currently implicated in 15-20% of cancer-related mortalities. This places obesity second only to smoking as the most […]

Find Out More

Mechanistic understanding of how obesity causes cancer – Research project #1: What are the properties of cancer cells adapted to aberrant physiological environments?

Obesity increases the risk of developing thirteen types of cancer that normal weight individuals may not develop despite of harbouring the same cancer risk loci. Globally, overweight/obesity may account for 544 300 cancer cases every year and is currently implicated in 15-20% of cancer-related mortalities. This places obesity second only to smoking as the most […]

Find Out More