The Cancer Drug Mechanisms Laboratory combines expertise in cell biology with understanding of drug mechanisms to treat cancers and other chronic diseases. The group’s cancer biology work currently focuses on understanding the development and progression of cancers of the skin and oral cavity. Specifically, the laboratory is investigating the molecular mechanisms involved in the progression and metastasis of melanoma, head and neck cancer, as well as cutaneous squamous cell carcinoma. These mechanisms also affect drug resistance of cancers. The identification and understanding of pathways in these cancers is crucial prior to the design or identification of suitable treatments. The group also uses its cell biology knowledge to assist in the development process for novel agents targeting cancer and other chronic disorders.
We gratefully acknowledge the support from the following funding agencies: