The Respiratory Immunology Laboratory focuses on identifying pathogenic pathways that underpin the onset, progression, and exacerbations of asthma and chronic obstructive pulmonary disease. To achieve this, high-fidelity preclinical models of disease are developed that recapitulate key gene-environment interactions and allow for elucidation of cellular and molecular mechanisms. Where possible, scientific findings are translated with ex vivo model systems using primary human cells and by analysing clinical material.
: Associate Professor Simon Phipps
- Dr Ashik Ullah, Research Officer
- Vivian Zhang, Postdoctoral Fellow
- Natasha Collinson,
- Ismail Sebina,
Associate Professor Simon Phipp’s complete list of publications can be viewed at his Google Scholar page.
- Eicosanoids and viral exacerbations of chronic obstructive pulmonary disease (COPD)
- ER stress pathways in respiratory disease
- Insights into the influence of maternal diet on the severity of infant viral bronchiolitis
- Cell death pathways and the induction of type-2 inflammation
- Microbiome and immune cell development in early life
- Regulation of HMGB1 and IL-33 release from airway epithelial cells
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