The Army Malaria Institute (AMI) Laboratory consolidates close collaborations between QIMR Berghofer and the Australian Defence Force Malaria and Infectious Disease Institute (ADFMIDI, formerly Australian Army Malaria Institute) that have existed for many years. The lab head, Dr Qin Cheng, was a QIMR scientist between 1989 and 1998, and has been a Visiting Scientist since 1998 after moving to ADFMIDI.
The laboratory consists of both QIMR Berghofer employees and ADFMIDI staff. The mission of the laboratory is to conduct biomedical research and to facilitate research collaborations between QIMR Berghofer and AMI. We focus on malaria research, with a particular interest in investigating biological and molecular changes that make parasites difficult to detect and more resistant to anti-malarial drugs. Our research outcomes inform malaria control and elimination policy and strategies.
The laboratory was initially established at QIMR in 2004 and called the Malaria Drug Resistance and Chemotherapy Laboratory (2004-2012). The laboratory was funded mainly from NIH and NHMRC grants. Between 2013 and 2016, we were part of the Clinical Tropical Medicine Laboratory at QIMR Berghofer.
Group Leader: Dr Qin Cheng
- Ms Karen Anderson, Technical staff
- Karryn Gresty, Research Assistant
- Dr Chris Peatey, Affiliate
Teuscher F, Gatton ML, Chen N, Peters J, Kyle DE, Cheng Q. 2010. Artemisinin-induced dormancy in Plasmodium falciparum: duration, recovery rates, and implications in treatment failure. J Infect Dis 202:1362-8.
Gamboa D, Ho MF, Bendezu J, Torres K, Chiodini PL, Barnwell JW, Incardona S, Perkins M, Bell D, McCarthy J, Cheng Q. 2010. A large proportion of P. falciparum isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: implications for malaria rapid diagnostic tests. PLoS One 5:e8091.
Gray KA, Dowd S, Bain L, Bobogare A, Wini L, Shanks GD, Cheng Q. 2013. Population genetics of Plasmodium falciparum and Plasmodium vivax and asymptomatic malaria in Temotu Province, Solomon Islands. Malar J 12:429.
Peatey CL, Chavchich M, Chen N, Gresty KJ, Gray KA, Gatton ML, Waters NC, Cheng Q. 2015. Mitochondrial membrane potential in a small subset of artemisinin-induced dormant Plasmodium falciparum parasites in vitro. J Infect Dis 212:426-34.
Berhane A, Anderson K, Mihreteab S, Gresty K, Rogier E, Mohamed S, Hagos F, Embaye G, Chinorumba A, Zehaie A, Dowd S, Waters NC, Gatton ML, Udhayakumar V, Cheng Q, Cunningham J. (2017) High Proportion of Plasmodium falciparum Parasites Lacking Histidine Rich Protein 2 (HRP2) in Eritrea Presents an Emerging Threat to Malaria Control Programs. Emerging Infectious Diseases (in press)
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