- 27 June 2019
1:00 pm - 2:00 pm
Thursday 27 june 2019, 1.00 PM
Auditorium, Level 6, BANCROFT Building
LARGE SCALE BRAIN DYNAMICS: MODELLING AND CLINICAL APPLICATIONS
Dr James Roberts,
QIMR Berghofer Medical Research Institute
The Brain Modelling Group models and analyses brain structure and dynamics, in health and disease. This talk will present three recent research directions we are pursuing. First, modelling of brain activity at the whole-brain scale. Our model of brain dynamics on the connectome (the brain’s wiring map) exhibits rich patterns of activity including “brain waves” that reconfigure dynamically over time, similar to experimentally observed patterns. Second, a novel infant functional brain development “growth chart”. Using brain activity recordings from infants born extremely prematurely, we have developed an automated method for tracking functional brain age with an accuracy of about ±2 weeks. And third, a multidisciplinary study linking infant sleep states to neurodevelopmental outcomes. Large-scale brain dynamics in pre- and full-term infants differ between quiet and active sleep states. These differences are attenuated by preterm birth and can be explained by a neural field model.
Dr James Roberts leads the Brain Modelling Group at QIMR Berghofer. He joined the Institute in 2010 after obtaining his PhD in physics at the University of Sydney. He was appointed as a Team Head in 2018. His research lies broadly in the field of computational neuroscience, at the intersection of physics, mathematics, neuroscience, and neurology. Dr Roberts employs a multidisciplinary approach that combines computational and analytical methods with clinical electrophysiological and neuroimaging data, to tackle complex problems in neuroscience and brain health.