Kidney cancer is the seventh most common cancer diagnosed in Australian men and eleventh most common cancer in women. The most common type of kidney cancer is renal cell carcinoma, accounting for about 90 % of all cases. Usually only one kidney is affected, but in rare cases the cancer may develop in both kidneys. In 2013, there were 962 deaths resulting from kidney cancer in Australia.
Research at QIMR Berghofer is aimed at developing a better understanding of the immune response to renal carcinoma and how that information can be translated into new cancer therapies.
Our research focuses on:
- the growth of renal cancer and its spontaneous metastasis to distant organs in mice, such the lung
- understanding why cancers growing in the kidney appear somewhat more resistant to immunotherapy
- examining the scheduling of immunotherapy treatment with surgery to try to cure renal cancer.
Our recent research has found:
- that renal cancers are more difficult to treat when growing under the kidney capsule and that multiple therapies may be required in combination.