The risk of developing a mental health disorder, such as schizophrenia, depression, autism, or drug/alcohol addiction is to a large extent influenced by genetic factors. More effective interventions could be developed if we understood the biological mechanisms of a disease. Large-scale genetic studies have revealed regions in DNA that contribute to disease risk, but the biological role of these regions is not yet well understood.
The study aims to:
- describe the functional role of genetic risk loci for mental health disorders
- identify functional targets for pharmacological interventions.
To conduct bioinformatics analyses to determine the impact of transcriptomic regulation (i.e., gene expression and epigenetic markers) on the development of mental health disorders. We aim to identify functionally relevant elements in regions of the DNA that have an impact on disease risk.
We are seeking a highly motivated student with a strong interest in statistics, bio-informatics, and quantitative studies.
What we offer
We offer a position in a dynamic research environment and the opportunity to conduct high-quality studies. Access to large-scale data sets through national and international collaborations. Be part of a successful research team.
- PhD project but may also be considered for a Honours project.
- Dry lab/bioinformatics project (not suitable for clinical students).