The Translational Neuroscience Group aims to develop sensitive and quantitative approaches to inform diagnosis and guide treatment in neuropsychiatric disorders. Our work combines advanced neuroimaging tools, such as MRI and EEG, with sensitive molecular biology techniques to examine neurobiological changes underlying cognitive and behavioural changes in diseases, and to understand fundamental questions about the human brain.
Team Head, Translational Neuroscience Group: Dr Christine Guo
- Vinh Nguyen, Research officer
- Taria Tane, Research assistant
- Yudan Ren, Visiting student
- Saurabh Sonkusare, PhD student
Guo CC, Tan R, Hodges JR, Hu X, Sami S, Hornberger M. Network-selective vulnerability of the human cerebellum to Alzheimer’s disease and frontotemporal dementia. (2016). Brain.
Guo CC, Hyett MP, Nguyen VT, Parker GB and Breakspear MJ. Distinct neurobiological signatures of brain connectivity in depression subtypes during natural viewing of emotionally salient films. Psychological Medicine. (Accepted).
Nguyen VT, Breakspear MJ, Hu X, Guo CC. The integration of the internal and external milieu in the insula during dynamic emotional experiences. (2016). NeuroImage.
Guo CC, Nguyen VT, Hyett MP, Parker GM, Breakspear MJ. Out-of-sync: disrupted neural activity in emotional circuitry during film viewing in melancholic depression. (2015). Scientific Reports.
Guo CC, Ke M, Raymond JR. Differential effects of visual target and background on motor learning in the VOR and climbing fiber instructive signals. (2014). J. Neurosci.
Guo CC, Gorno-Tempini ML, Gesierich B, Henry M, Trujillo A, Shany-Ur T, Jovicich, J, Robinson SD, Kramer JH, Rankin KP, Miller BL, Seeley WW. Anterior temporal lobe degeneration produces widespread network-driven dysfunction (2013). Brain.
Guo CC, Kurth F, Zhou J, Mayer EA, Eickhoff SB, Kramer JH, Seeley WW. One-year test-retest reliability of intrinsic connectivity network fMRI in older adults (2012). NeuroImage.
Ke M*, Guo CC*, Raymond JR. Elimination of climbing fiber instructive signals during motor learning. (2009). Nature Neuroscience. * Equal contribution
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