The Translational Neurogenomics Laboratory investigates the role of genetic factors in a range of psychiatric conditions, including schizophrenia, addiction, anxiety disorders and compulsive disorders. By researching a wide variety of symptoms that are typical of patients with a particular psychiatric condition, they can use newly developed statistical methods to discover associations between the condition and genetic variants.
To fully identify and understand the biological processes that result in a psychiatric condition, the lab:
- studies genetic variation
- identifies differences in gene expression levels observed in brain and non-brain tissues
- finds associations between genetic risk and brain anatomy.
Translational Neurogenomics refers to two topics that are equally important in the study of psychiatric disorders:
- The translation of genetic code to RNA and proteins.
- The translation of research findings to the clinic (from bench to bed).
- What causes overlap between mental health disorders?
- What makes one at risk for having a mental health disorder? Investigating the regulatory role of genetic variants
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