The Cellular Immunology Group focuses on the T cell immune response to viral infection, particularly Epstein-Barr virus which causes glandular fever and is associated with various malignancies and autoimmunity. The molecular interactions that control the specificity of T cells recognition of virus-infected cells are complex and could hold the key to preventing Epstein-Barr virus associated diseases.
We also investigated the strategies used by EBV to evade immune recognition, and examined the basis for the apparent link between Epstein-Barr virus infection and multiple sclerosis.
By investigating the interaction of our immune system with EBV (a virus that remains in our body for life) it provides insights into how we can combat glandular fever and EBV-related cancers such as nasopharyngeal carcinoma and Hodgkin’s lymphoma.
The laboratory’s main focus is the cytotoxic T lymphocyte and factors controlling its primary function in recognising and killing virus-infected cells.
Group Leader: Professor Scott Burrows
- Melissa Rist, Post PhD Submission Student
- Jacqueline Burrows, Senior Laboratory Coordinator
- Dr Michelle Neller, Clinical Trials Manager
- Dr Rebekah Brennan, Research Officer
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